GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs4665809 | 1 | rs4665309 | chr2:26335502 | GPR113 | chr2:26531041-26569685:- | -0.42 | -6.71 | 5.42E-11 | Gut microbiome composition (summer) |
| THCA | cis | rs6547741 | 1 | rs4665381 | chr2:27757150 | FNDC4 | chr2:27714751-27718126:- | -0.15 | -3.54 | 0.000436 | Oral cavity cancer |
| THCA | cis | rs1561288 | 1 | rs4665768 | chr2:25372229 | POMC | chr2:25383722-25391559:- | 0.25 | 4.1 | 4.91E-5 | Body mass index |
| THCA | cis | rs4665809 | 1 | rs4665809 | chr2:26251361 | GPR113 | chr2:26531041-26569685:- | 0.44 | 6.98 | 9.61E-12 | Gut microbiome composition (summer) |
| THCA | cis | rs4665809 | 1 | rs4665811 | chr2:26260017 | GPR113 | chr2:26531041-26569685:- | -0.43 | -6.74 | 4.43E-11 | Gut microbiome composition (summer) |
| THCA | cis | rs4665809 | 1 | rs4665811 | chr2:26260017 | HADHA | chr2:26413505-26467594:- | -0.16 | -3.35 | 0.000874 | Gut microbiome composition (summer) |
| THCA | cis | rs4665809 | 1 | rs4665816 | chr2:26305094 | GPR113 | chr2:26531041-26569685:- | -0.42 | -6.7 | 5.97E-11 | Gut microbiome composition (summer) |
| THCA | cis | rs4665809 | 1 | rs4665816 | chr2:26305094 | HADHA | chr2:26413505-26467594:- | -0.16 | -3.35 | 0.00088 | Gut microbiome composition (summer) |
| THCA | cis | rs4665809 | 1 | rs4665817 | chr2:26305167 | GPR113 | chr2:26531041-26569685:- | -0.48 | -7.36 | 8.07E-13 | Gut microbiome composition (summer) |
| THCA | cis | rs4665809 | 1 | rs4665817 | chr2:26305167 | HADHA | chr2:26413505-26467594:- | -0.17 | -3.44 | 0.000643 | Gut microbiome composition (summer) |
| THCA | cis | rs4665809 | 1 | rs4665819 | chr2:26309073 | GPR113 | chr2:26531041-26569685:- | -0.45 | -7.05 | 6.34E-12 | Gut microbiome composition (summer) |
| THCA | cis | rs4665809 | 1 | rs4665820 | chr2:26309150 | GPR113 | chr2:26531041-26569685:- | -0.45 | -7.05 | 6.34E-12 | Gut microbiome composition (summer) |
| THCA | cis | rs4665809 | 1 | rs4665821 | chr2:26309949 | GPR113 | chr2:26531041-26569685:- | -0.45 | -7.05 | 6.34E-12 | Gut microbiome composition (summer) |
| THCA | cis | rs4665809 | 1 | rs4665823 | chr2:26312723 | GPR113 | chr2:26531041-26569685:- | -0.45 | -7.05 | 6.34E-12 | Gut microbiome composition (summer) |
| THCA | cis | rs1395 | 1 | rs4665958 | chr2:27443196 | C2orf28 | chr2:27434899-27440044:+ | 0.16 | 4.82 | 1.89E-6 | Blood metabolite levels |